Guided by Deep
Scientific Expertise &
Driven by a Passion
to Deliver For Patients

We are focused on harnessing the power of the TGF-beta superfamily, the target-rich biology behind the body’s remarkable capacity for cellular growth and repair. Our insights and protein engineering capabilities enable us to design first- and best-in-class candidates for serious and rare hematologic, neuromuscular, and pulmonary diseases.

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Our Diverse Pipeline is Fueled by a Unique Understanding of TGF-Beta Biology


Hematology

Luspatercept

Hematology

Luspatercept
PreclinicalPhase 1Phase 2Phase 3
Myelodysplastic Syndromes
Myelodysplastic
Syndromes
MEDALIST Trial*MEDALIST Trial*
COMMANDS Trial*COMMANDS Trial*
Long-Term Extension TrialLong-Term Ext Tr
Beta-Thalassemia
Beta-Thalassemia
BELIEVE Trial*BELIEVE Trial*
Long-Term Extension TrialLong-Term Ext Tr
BEYOND Trial*BEYOND Trial*
Myelofibrosis
Myelofibrosis
Ph2 Trial*Ph 2*

* Celgene-sponsored


Neuromuscular

ACE-083
PreclinicalPhase 1Phase 2Phase 3

Neuromuscular

ACE-083
FSH Muscular Dystrophy
FSH Muscular Dystrophy
Ph2 TrialPh2
Charcot-Marie-Tooth Disease
Charcot-Marie-Tooth Disease
Ph2 TrialPh 2
ACE-2494
Neuromuscular Disease
Neuromuscular Disease
Ph1 TrialPh 1


Pulmonary

Sotatercept
PreclinicalPhase 1Phase 2Phase 3

Pulmonary

Sotatercept
 
Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension
PULSAR TrialPULSAR Trial
SPECTRA Exploratory Trial (Planned)SPECTRA (Planned)
ACE-1334
Pulmonary Disease
Pulmonary Disease
PreclinicalPreclinical
Acceleron Pharma

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