Mr. Dable joined Acceleron in December 2016 as the Company’s President and Chief Executive Officer and member of its Board of Directors.
Mr. Dable most recently served as President of U.S. Pharmaceuticals at Bayer AG. During his 22-year tenure there, Mr. Dable held positions of increasing responsibility. In addition to President of U.S. Pharmaceuticals, he also served as Executive Vice President, Global Head Specialty Medicine; Vice President, Ophthalmology, Global Launch Team Head, EYLEA®, Global Head, Neurology and Ophthalmology; Vice President, Regional Head, Hematology and Cardiology; Director of International Sales and Marketing, Biologics Research; and Head of Strategic Planning, Pharmaceuticals, Japan. Mr. Dable’s earlier experience at Bayer AG includes various sales and sales management positions in Canada.
As Executive Vice President, Global Head Specialty Medicine, Mr. Dable led the launch of various blockbuster brands, including EYLEA®, Stivarga®, and Xofigo®. Mr. Dable also managed research and development collaborations and served on Joint Steering Committees with companies such as Algeta ASA, Orion Corporation and Regeneron Pharmaceuticals.
Mr. Dable most recently served on the Board of Directors of the Biotechnology Innovation Organization (BIO).
Mr. Dable received a BBA in Marketing and Finance and his MBA from the University of New Brunswick.
Francois Nader, MD, is currently the chairman of Acceleron Pharma and a leading value builder in the biopharma industry. He was President, Chief Executive Officer and Executive Director of NPS Pharma from 2008 to 2015, when the company was acquired by Shire for $5.2B. During his tenure as CEO Dr. Nader transformed NPS Pharma into a leading global biotechnology company focused on delivering innovative therapies to patients with rare diseases. He was recognized as the Ernst and Young National Life Science Entrepreneur of the Year® in 2013. Dr. Nader currently serves as chairman of the board of directors of Acceleron Pharma (NASDAQ: XLRN) and board director of Alexion Pharmaceuticals (NASDAQ: ALXN), Clementia Pharmaceuticals (NADAQ: CMTA) and ArRETT Neurosciences.
Before NPS, Dr. Nader was a venture partner at Care Capital. Prior, he served on the North America Leadership Team of Aventis and its predecessor companies holding a number of executive positions including senior vice-president, integrated healthcare markets and North America medical and regulatory affairs. Previously, he led the global commercial operations at the Pasteur Vaccines division of Rhone-Poulenc.
Dr. Nader is a recognized leader in industry and philanthropic organizations. He is the President of the Jesra Foundation, a trustee of the New Jersey Chamber of Commerce and sits on the Advisory Board of the Open Future Institute. He is a past chairman of BioNJ, New Jersey’s biotechnology trade organization, and has served on the board of the Biotechnology Industry Organization (BIO), the national industry body, NPS Pharma (NASDAQ: NPSP), Advanced Accelerator Applications (NASDAQ: AAAP), Baxalta (NYSE: BXLT), Trevena (NASDAQ: TRVN) and Noven (NASDAQ: NOVN).
Dr. Nader earned his French Doctorate in Medicine from St. Joseph University in Lebanon and his Physician Executive MBA from the University of Tennessee.
Ms. George has served as a member of Acceleron’s board of directors since 2005. Since 2002, Ms. George has been a Managing Director at Advanced Technology Ventures (ATV), and, concurrently since April 2013, Ms. George has been a Managing Director at LSV Capital Management. She joined ATV in 2002 and serves as the firm’s East Coast lead partner for healthcare investments. Prior to joining ATV, Ms. George was a Director at BancBoston Ventures, where she led the health care team’s investment activity in NuGenesis Technologies Corp., Microbia, Inc., Syntonix Pharmaceuticals, Inc. and Neurometrix, Inc. Before BancBoston Ventures, she worked at Genzyme Corporation from 1988 to 1998, where she held a variety of operational roles in marketing, product development, and business development, including Vice President of Global Sales and Marketing. She also worked as a Vice President and Founder of Genzyme’s Tissue Repair Division. She is currently a Director of Calithera Biosciences, Hydra Biosciences, Inc., Zeltiq Aesthetics, Inc. and Portola Pharmaceuticals, Inc. Ms. George was a Director of Hypnion, Inc., Critical Therapeutics, Inc. and Proteolix, Inc. She was named a member of the Scientific Advisory Board for the Massachusetts Life Sciences Center. Ms. George received a BS in biology from the University of Maine and an MBA from Simmons College Graduate School of Management.
Terrence C. Kearney has more than three decades of global healthcare experience at major pharmaceutical and life sciences companies. Most recently, Mr. Kearney served on the executive management team for Hospira, Inc. where he held the role of Chief Operating Officer from 2006 through 2011 and Chief Financial Officer from 2004 to 2006. In these roles, Mr. Kearney had broad responsibility for the company’s global operations, including commercial, manufacturing and research and development activities, and financial management strategies. Prior to Hospira, Mr. Kearney spent 25 years at Abbott Laboratories in various financial management roles, including Vice President and Treasurer. Mr. Kearney earned a Bachelor’s degree in Biology from the University of Illinois and a Master’s in Business Administration from the University of Denver. Mr. Kearney serves as Chair of the Audit Committee and member of the Management Development and Compensation Committee for Vertex Pharmaceuticals.
Dr. Maniatis co-founded Acceleron in 2003 and has served as a member of Acceleron’s board of directors and chairman of Acceleron’s Scientific Advisory Board since 2003. Since 2010 he has been a Professor and Chair of the Department of Biochemistry & Molecular Biophysics at the Columbia University College of Physicians and Surgeons. Prior to working at Columbia, Dr. Maniatis was a professor at Harvard University where he studied the mechanisms of transcription and RNA splicing in eukaryotes. Dr. Maniatis currently serves on the board of Constellation Pharmaceuticals, Inc. Dr. Maniatis is also a co-founder of Genetics Institute and ProScript Inc., where he served on the board of directors. Dr. Maniatis is a member of the U.S. National Academy of Sciences, and has received numerous awards for his research contributions, including the Eli Lilly Research Award in Microbiology and Immunology, the Richard Lounsbery Award for Biology and Medicine from the U.S. and French National Academies of Science, and the 2012 Lasker-Koshland Special Achievement Award in Medical Science. Dr. Maniatis received a BA in biology, an MS in chemistry from the University of Colorado at Boulder, and a Ph.D. in molecular biology from Vanderbilt University.
Mr. McCourt joined Acceleron’s board of directors in 2016. He has 30 years of experience building commercial strategies and capabilities for new therapies at multiple pharma and biotech companies. Mr. McCourt serves as the chief commercial officer and senior vice president of marketing and sales at Ironwood Pharmaceuticals, Inc., where he led the commercial launch of LINZESS®. Prior to joining Ironwood in 2009, Mr. McCourt oversaw the U.S. brand team for denosumab at Amgen Inc. Before that, he held a number of senior commercial roles at Novartis AG, where he directed the launch and growth of ZELNORM®. He was also vice president of strategic marketing and operations during his tenure at Novartis AG.
Earlier in his career, Mr. McCourt was part of the founding team at Astra Merck Inc., leading the development of the medical affairs and science liaison group and serving as brand manager for PRILOSEC® and NEXIUM®. He earned a degree in pharmacy from the University of Wisconsin, where he serves as a member of the Board of Visitors for the School of Pharmacy.
Mr. Pops has served as a member of Acceleron’s board of directors since 2004. Since 2009, Mr. Pops has served as Chief Executive Officer and Chairman of the board of Alkermes. From 2007 to 2009 he served as the Chairman of the board of Alkermes, and from 1991 through 2007 he served as the Chief Executive Officer of Alkermes. Mr. Pops also serves on the board of directors of Neurocrine Biosciences, Inc., Epizyme, Inc., the Biotechnology Industry Organization and Pharmaceutical Researcher and Manufacturers of America. He has previously served on the board of directors of Sirtris Pharmaceuticals from 2004 to 2008, and CombinatoRx, Inc. from 2001 to 2009. Mr. Pops also served on the board of directors of Reliant Pharmaceuticals, a privately held pharmaceutical company purchased by GlaxoSmithKline in 2007, and on the advisory board of Polaris Venture Partners. He was a member of the Harvard Medical School Board of Fellows from 2002 through June 2012. Mr. Pops received a BA in economics from Stanford University.
Dr. Karen Smith joined Acceleron’s board of directors in 2017. Most recently, Dr. Smith served as Executive Vice President, Global Head R&D, and Chief Medical Officer of Jazz Pharmaceuticals, Inc. Prior to joining Jazz Pharmaceuticals, Dr. Smith was Senior Vice President, Global Medical Affairs and Global Dermatology Head for Allergan. She also held senior positions in External Medical Relations and Global Development at AstraZeneca. Before that, she held a variety of management and medical roles with Bristol-Myers Squibb, most recently as the Head of U.S. Clinical Operations. Dr. Smith earned a B.App.Sc. and a B.Sc. (Honors) from the Curtin University of Technology, an M.D. from the University of Warwick, a Ph.D. in oncology molecular genetics from the University of Western Australia, an M.B.A. from the University of New England (Australia) and a L.L.M. in medical law from the University of Salford.
Mr. Zakrzewski has served as a member of our board of directors since March 2011. Mr. Zakrzewski had been Executive Chairman and Chief Executive Officer of Amarin Corporation. From 2007 to 2010, Mr. Zakrzewski served as President and Chief Executive Officer of Xcellerex. From 2005 to 2007, Mr. Zakrzewski served as the Chief Operating Officer of Reliant Pharmaceuticals, overseeing the launch of Omacor®, a drug to treat elevated triglyceride levels. From 1988 to 2004, Mr. Zakrzewski served in a variety of positions at Eli Lilly and Company including as Vice President, Corporate Business Development from 2003 through 2004. In addition, Mr. Zakrzewski served as a Venture Partner with OrbiMed in 2010 and 2011. Mr. Zakrzewski also currently serves on the board of directors of Amarin and Insulet Corporation and has also served on the board of directors of Xcellerex, Azelon/Zelos Therapeutics and Promedior. Mr. Zakrzewski received a BS in Chemical Engineering and an MS in Biochemical Engineering from Drexel University as well as an MBA in Finance from Indiana University.