Pipeline

Pulmonary

Pulmonary

Titletitle
Phase 1Ph1
Phase 2Ph2
Phase 3Ph3
ApprovedAppd

Sotatercept

Pulmonary Arterial Hypertension

Sotatercept

Pulmonary Arterial Hypertension
STELLAR TrialSTELLAR
HYPERION TrialHYPERION
ZENITH TrialZENITH
SOTERIA TrialSOTERIA
PULSAR TrialPULSAR
SPECTRA TrialSPECTRA
WHO Group 2 Pulmonary Hypertension
WHO Group 2 Pulmonary Hypertension
CADENCE Trial (planned)CADENCE

ACE-1334

SSc-ILD

ACE-1334

SSc-ILD
Ph 1b/2 Ph 1b/2

Hematology

Hematology

Titletitle
Phase 1Ph1
Phase 2Ph2
Phase 3Ph3
ApprovedAppd

REBLOZYL®
(luspatercept-aamt)

Myelodysplastic Syndromes

REBLOZYL®
(luspatercept-aamt)

Myelodysplastic Syndromes
Beta-Thalassemia
Beta-Thalassemia

luspatercept-aamt

Myelodysplastic Syndromes

luspatercept-aamt

Myelodysplastic Syndromes
COMMANDS Trial*+COMMANDS*+
Beta-Thalassemia non-transfusion dependent
Beta-Thalassemia non-transfusion dependent
BEYOND Trial*BEYOND*
Myelofibrosis
Myelofibrosis
INDEPENDENCE Trial*INDEPENDENCE*

* Bristol Myers Squibb-sponsored

+ Now enrolling: COMMANDS. A Phase 3 trial for patients with low- or intermediate-risk MDS