Our Pipeline

Science & Pipeline

Pulmonary

Sotatercept

Pulmonary Sotatercept
	Phase 1Ph1	Phase 2Ph2	Phase 3Ph3	ApprovedApp
Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension	STELLAR Trial (planned)STELLAR Trial (planned)STELLAR HYPERION Trial (planned)HYPERION Trial (planned)HYPERION ZENITH Trial (planned)ZENITH Trial (planned)ZENITH PULSAR TrialPULSAR TrialPULSAR SPECTRA TrialSPECTRASPECTRA

Pulmonary

ACE-1334

	Phase 1Ph1	Phase 2Ph2	Phase 3Ph3	ApprovedApp
ACE-1334
SSc-ILD
SSc-ILD	Ph 1b/2 (planned)Ph 1b/2 (planned)Ph 1b/2

Hematology

	Phase 1Ph1	Phase 2Ph2	Phase 3Ph3	ApprovedApp
Hematology REBLOZYL^® (luspatercept-aamt)
	REBLOZYL^® (luspatercept-aamt) Myelodysplastic Syndromes
Myelodysplastic Syndromes
	Beta-Thalassemia
Beta-Thalassemia

luspatercept-aamt

luspatercept-aamt
luspatercept-aamt
	Myelodysplastic Syndromes
Myelodysplastic Syndromes	COMMANDS TrialCOMMANDS TrialCOMMANDS*
	Beta-Thalassemia non-transfusion dependent
Beta-Thalassemia non-transfusion dependent	BEYOND TrialBEYOND TrialBEYOND*
	Myelofibrosis
Myelofibrosis	INDEPENDENCE Trial (planned)INDEPENDENCE Trial (planned)INDEP*

* Bristol Myers Squibb-sponsored